High-quality peptide drug Bronchogen 20mg/vial

Bronchogen (AEDL) is a synthetic tetrapeptide biomodulator targeting the respiratory tract, composed of four amino acids (alanine A, glutamic acid E, aspartic acid D, and leucine L). Its core functions are repairing bronchial epithelium, anti-inflammation, maintaining lung function, and delaying respiratory tissue aging; it is known as a "lung repair peptide." It is a core product of the Russian Khavinson short-peptide biomodulation system, primarily targeting respiratory system maintenance and assisting in the improvement of chronic airway problems.

Research Origin: In the 1970s, Soviet military medical research initiated a short-peptide biomodulation project. In the 1990s, Professor Vladimir Khavinson's team at the St. Petersburg Institute of Biomodulation and Gerontology in Russia identified and synthesized Bronchogen (AEDL), mimicking the regulatory functions of natural peptide fragments in human bronchial tissue.

Core Positioning: As a bronchial tissue-specific biomodulator, it forms a golden combination with Chonluten (EDG tripeptide) for the respiratory tract; the former focuses on epithelial repair, while the latter focuses on anti-inflammatory stress.

Application Implementation: Approved in Russia as an oral capsule dietary supplement, and circulated in Europe and the US as a research-grade freeze-dried powder for research on respiratory aging, chronic bronchitis, and COPD.

October 2025: Research progress published in *BioLongevity Labs* confirmed that Bronchogen can directly bind to DNA and histones, regulating bronchial epithelial differentiation and surfactant synthesis, representing a new epigenetic anti-aging target.

March 2026: Clinical observation by the Russian Geriatrics Society showed that patients over 60 years of age with chronic bronchitis who took Bronchogen for 30 days experienced an average increase of 12%-15% in lung function indicators (FEV1, FVC), and significant relief of cough and shortness of breath symptoms.

April 2026: The research market in Europe and the US is heating up; Bronchogen has been included as a key research peptide for lung aging and post-COVID-19 lung injury repair, and multiple laboratories have initiated preliminary human safety trials.

Chinese Name: Bronchogen-Regulating Peptide / Lung-Repairing Peptide

Amino Acid Sequence: Ala-Glu-Asp-Leu (Alanine - Glutamic Acid - Aspartic Acid - Leucine)

Molecular Weight: 446.45 Da
Purity: >=98% (Research Grade), >=99% (Pharmaceutical Grade)

Half-life: Short (several minutes), action is sustained through epigenetic regulation

Storage: Powder - 20℃, sealed and protected from light; capsules at room temperature; after reconstitution, dispense at -70℃, avoid repeated freeze-thaw cycles

Dosage Form: Lyophilized powder (5mg/10mg/20mg/bottle), oral capsules (10mg/capsule)

1) Oral (Daily Maintenance/Mild Inflammation)

Regular: 10-20 mg/day (1-2 capsules), on an empty stomach or with meals in the morning, 20-30 days as one cycle, with a 10-day break before repeating.

Elderly/Chronic Bronchitis: 20 mg/day, divided into 2 doses, 30 days as one cycle, for 2-3 consecutive cycles.

2) Subcutaneous Injection (Severe Lung Injury/COPD/Postoperative Repair)

Beginner: 500 ug/day, subcutaneous injection in the abdomen, 2 hours after meals in the evening, 40 days as one cycle.

Advanced: 1000 ug/day, 6 days on, 1 day off, 7 weeks as one cycle.

Combination: For better results, use in combination with Chonluten (EDG), Bronchogen 500 ug/day + Chonluten 300 ug/day.

Bronchoalveolar Epithelial Repair: Targets type II bronchial and alveolar cells, activates epithelial differentiation genes, repairs damaged ciliated epithelium, reduces goblet cell proliferation, and restores the airway mucosal barrier.

Powerful Anti-inflammatory: Inhibits inflammatory pathways such as NF-κB, reduces inflammatory factors such as IL-6 and TNF- , and alleviates chronic airway inflammation and edema.

Lung Function Maintenance: Promotes the synthesis of pulmonary surfactant, maintains alveolar elasticity, increases FEV1/FVC, and improves ventilation efficiency.

Anti-aging and DNA Protection: Stabilizes the DNA double helix (increases unwinding temperature by 3.1℃), delays telomere shortening, and reverses age-related lung function decline.

Enhanced Mucociliary Clearance: Regulates mucin gene expression, thins sputum, promotes expectoration, and reduces airway obstruction.

Immune Regulation: Balances local respiratory immunity, enhances mucosal resistance, and reduces the risk of recurrent respiratory infections.

Highly Targeted: Precisely acts on bronchial/alveolar tissue without affecting other organs, resulting in extremely low side effects.

Unique Mechanism: Directly binds to DNA to regulate gene expression, repairing tissue at its root rather than simply alleviating symptoms.

Endogenous Homologous: Mimics natural peptide fragments in the human body, exhibiting good tolerability, no immunogenicity, and no addictive properties.

Synergistic Effects: Simultaneously achieves repair + anti-inflammation + anti-aging + immune regulation, suitable for comprehensive treatment of chronic respiratory problems.

High Safety: No serious adverse reactions observed in animal experiments and human observations, suitable for the elderly.

High Combination Value: When used in combination with Chonluten, thymosin, etc., the effects are synergistic, suitable for complex respiratory problems.

Limited Human Clinical Data: No large-scale Phase III clinical trials; existing evidence is mostly from animal experiments and small-sample observations in Russia; long-term efficacy remains to be verified.

Mild Action, Long Cycle: Not a fast-acting drug; requires 2-4 weeks of continuous treatment to show effects, unsuitable for acute critical care.

**High Price:** The cost of research-grade powder and imported capsules is higher than that of ordinary lung-nourishing health products.

**Individual Differences:** Approximately 5%-10% of people may not experience significant effects, possibly related to genetics or the severity of underlying diseases.

**Compliance Limitations:** There is no formal drug approval globally; it is only used as a research reagent/dietary supplement and cannot replace drug treatment.

**Chronic Respiratory Diseases:** Chronic bronchitis, COPD, mild asthma, bronchiectasis (aids in symptom improvement and reduces acute attacks).

**Lung Aging and Aging:** Individuals over 45 years of age experiencing natural decline in lung function, shortness of breath after activity, and susceptibility to colds.

**Respiratory Tract Damage Repair:** Lung damage after COVID-19, recovery period from pneumonia, lung damage caused by smoking/smog, and postoperative airway repair.

**Low Immunity:** Recurrent colds, seasonal coughs, and children/elderly individuals with respiratory susceptibility.

**Occupational/Environmental Exposure:** Lung care for individuals with long-term exposure to dust, chemical gases, and secondhand smoke.

Anti-aging and Health Management: Targeting high-end anti-aging individuals seeking to rejuvenate their respiratory system and delay aging.

Contraindications: Patients with malignant tumors, pregnant women, breastfeeding women, adolescents under 18 years of age, and those with severe liver or kidney dysfunction are prohibited from use.

Use with Caution: Individuals with autoimmune diseases, acute respiratory infections, or abnormal coagulation function require professional guidance.

Dosage Guidelines: Prepare the powder for injection immediately and reconstitute it with sterile water for injection to avoid contamination.

Subcutaneous injection: Choose the abdomen/lateral thigh, rotating injection sites to reduce local irritation.

Cycle Management: Continuous use should not exceed 8 weeks. Discontinue use for 10-14 days to avoid receptor desensitization; long-term maintenance can be achieved through intermittent cycles.

Combined Contraindications: Avoid combined use with high-dose glucocorticoids or immunosuppressants, as this may affect efficacy.

Monitoring Indicators: Regularly check lung function, blood routine, and inflammatory factors to assess efficacy and safety.

Compliance Notice: This product is a research-grade reagent/dietary supplement, not a drug. It cannot replace antibiotics, bronchodilators, or other medications. Seek medical attention promptly for acute attacks.

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